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According to our study, we proved that meldonium could improve neurological function, considerably lessen pathological neuronal injury in the cortex and hippocampus, and reduce infarct volume in MCAO rats

The acetyl-CoA necessary for cytosolic fatty acid synthesis in cells in the brain, particularly oligodendrocytes (myelin producing cells), is derived from N -acetylaspartate (NAA), not from citrate as is the case for other tissues

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