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Reports of artemisinin resistance in Southeast Asia and Africa underscore the need for natural strategies that reduce the parasites capacity to adapt [3,4,5,6,7]

11f), consistent with the triglyceride synthesis observed in this study

To further understand the role played by the RRM2 gene in the whole biological behavior of tumors, we performed a pan-cancer analysis by the combination of TCGA and GTEx data, which showed that RRM2 was generally highly expressed in tumors of epithelial origin, such as THCA, esophageal carcinoma, and breast carcinoma, suggesting that its pro-carcinogenic mechanism is conserved by the cancer species

Collagenase solution was added and shaking was performed on a shaker for 3 min at 1700 rpm, followed by incubation in a 37 C water bath for 5 min, alternating 10 times
