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(2020) 30:34113423.e7

For example, low concentrations of HO promote cell survival by inhibiting the phosphatase PTEN and activating the PI3K/Akt pathway, while superoxide anions (O) produced by NOX 2 in macrophages induce pro-inflammatory cytokine expression via NF-B signaling to enhance antimicrobial immunity 18,19,20
