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doi:10.1016/j.heares.2015.01.002

In addition, the docking scoring function mainly evaluates static binding affinity, which makes it tough to accurately simulate the complex physiological environment in living organisms (such as solvation effects, entropy changes, etc.), which might result in false positives in experiments for molecules that are predicted to bind well (Gioia et al., 2017

Our findings have thus not only documented the role of a deubiquitylase in erythropoiesis, but also enabled the identification of a novel mechanism by which deubiquitylases regulate GATA1 protein stability

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Unlike skin, where pigment production is a constant process, hair pigmentation is closely tied to the phases of the hair growth cycle