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Description
Iondipol interactions with water molecules cause reverse addictionproportional between the charge on the chromophore and its affinity for hydrophobic expulsion
For example, the linker structure of SAR-3419 was fine-tuned for optimal antitumoral activity selecting SPDB-DM4, which displays a gem-dimethyl substitution on the payload side
doi: 10.1042/bj3220213
10.3389/fimmu.2023.1275890 18 CortatY.ZobiF
A few cross the blood-brain barrier with remarkable efficiency, delivering their signals directly to injured tissue
