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SIRT1 is also known as the "longevity gene" because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer

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These include symptomatic improvement, notably in sputum characteristics, i.e., it reduces viscosity and volume ( 1 ) and Peak Expiratory Flow Rate (PEFR) ( Initial studies utilizing low-dose NAC (600 mg/day) yielded promising results, prompting the initiation of larger multicenter RCTs focused on GOLD-defined COPD patients