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doi: 10.36849/JDD.2020.5079
10.1016/j.mib.2018.02.002 130
In contrast, ROXY9 encodes a glutamate, the negative charge of which may even lead to repulsion of the ligand
The disease is caused by the CAG trinucleotide expansion in the Huntingtin gene (HTT), which results in an expanded polyglutamine repeat in the Htt protein [196]
Mechanistically, plumbagin interferes with the YTHDF1-mediated m 6 A methylation pathway that regulates SLC7A5 translation (84)
