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Warnings and Precautions Pregnancy and breast-feeding: Vitamin C is likely safe for pregnant or breast-feeding women when taken by mouth in amounts no greater than 2000mg daily for women over 19 years old, and 1800mg daily for women 14-18 years old, or given intramuscularly or intravenously

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Whether this reflects genuine cardiovascular benefit or simply the healing of minor injuries that were limiting exercise capacity remains unclear

PDHc Kinases The activity of PDH (E1) is rapidly regulated by phosphorylation and dephosphorylation events that are catalyzed by PDH kinases (PDK) and PDH phosphatases (PDP), respectively