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Some people start with a more frequent schedule, then move to a maintenance visit once their levels are steady

14 Therefore, the halflife of salicylate depends on the major metabolic pathway used at a given concentration, and becomes longer with increasing dosage

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These values account for 14% and 54% of the calculated V max , respectively, and match with the observed almost 4-fold stimulation of GSH export in ritonavir-treated astrocytes