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Moreover, a low-iLe diet can quickly restore the metabolic health of obese mouse models induced by a high-fat diet

Since renal medullary cells, whose role is to concentrate urine, are constantly exposed to extremely high levels of sodium chloride and urea, the accumulation of betaine in renal medullary cells helps balance the hypertonicity in interstitial fluid (Kempson et al., 2014)

Furthermore, incubation of vitamin C with virus-infected human and murine fibroblasts enhanced generation of antiviral IFN [91,92,93]

Lymphocytes play a key role in fighting viral infections and regulating immune responses

Liver biopsy, may be helpful in identifying liver disease pattern and ruling out of some disease pathologies, is unnecessary