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For one, it makes a robust clinical trial logistically tricky, said Christopher Milne, past director of research at the Tufts Center for the Study of Drug Development
Jastreboff et al., 2022) documented superior weight loss and glycemic control compared to single-target GLP-1 agonists, with up to 22.5% body weight reduction at 72 weeks in the SURMOUNT-1 trial

The peptide does not bind to a single identified receptor but instead modulates several biological systems simultaneously

Kennedy and his MAHA allies claim that these peptides can help with concerns ranging from muscle gain to weight loss
