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Systematic literature review and evidence grading The methodology used for collecting the evidence base for this guideline is essentially that used by the Scottish Intercollegiate Guideline Network (SIGN, A systematic literature review on MMA/PA from the time of description of each disease until December 2011 was carried out using mainly Medline, Embase, the Cochrane Library, MedLink, and Orphanet

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It is a central nervous system (CNS) stimulant medication that can result in focus enhancement, cognitive improvement, and concentration, making it easier for those with ADHD to navigate work, academics, or any aspect of daily life