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When Wnt proteins bind to their cell-surface receptors (Frizzled and LRP5/6), the destruction complex is inhibited, allowing -catenin to accumulate and enter the nucleus, where it activates Wnt target gene expression through interaction with T-cell factor (TCF) transcription factors
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The ZRT Laboratory Blog , Accessed May 30, 2022.
Fujii, Curr
A microwave oven performed heat-induced epitope retrieval
