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Chapman LE, Darling AL, Brown JE (2015) The association between the biguanide drug metformin and vitamin B 12 deficiency in diabetic patients: a systematic review

During spermatogenesis, the sperm undergoes molecular remodeling at the nuclear level essential to reduce cell volume and protect the genetic content [28]

Nonspecific immunosuppressants derived from classical chemotherapeutic agents, such as azathioprine, mitoxantrone and cyclophosphamide, which are not routinely used for MS, indiscriminately reduce the proliferation of all rapidly dividing cells, including immune cells

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successfully treated a COVID-19 patient with intrahepatic haemorrhage with the application of IV NAC [180]
