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An overview of recent developments in the field of nanoparticle-mediated CNS drug delivery and a brief discussion of significant hurdles to drug delivery to the CNS and the progress made so far in overcoming such hurdles for traditional CNS therapies have been attempted here

(2024) 386:e078635

Front Psych

Future studies using melatonin-competent mice, genetic validation of receptor independence, and time-of-day dosing paradigms will be critical to determine whether the melatoninglutathione axis can be exploited therapeutically to treat asthma

Specifically, a review of clinical trials on the use of BPC-157 has characterized it as safe both in treating inflammatory bowel disease and wound healing, noting that no events of toxicity had been reported throughout those trials [12]