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Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells

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Timeline and Requirements to Respond to an FDA 483 The FDA expects a timely and complete response to every Form 483 issued

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J Immunotoxicol (2005) 2 (1):1120

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Smith PD, Smythies LE, Mosteller-Barnum M, Sibley DA, Russell MW, Merger M, Sellers MT, Orenstein JM, Shimada T, Graham MF, Kubagawa H: Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activities

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