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When vitamin B12 is released from foods by peptic digestion, it is bound to intrinsic factor, affording partial protection against gut microorganisms and parasites during transport through the gut to the terminal ileum, where the complex binds to microvilli of the intestinal epithelial cells

pmid:34140279FREE Full TextGoogle Scholar Metformin and reduced vitamin B12 levels: new advice for monitoring patients at risk

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Dark Urine Hydration plays a central role in determining urine color: Pale yellow or clear urine is typically a sign of good hydration
