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While studies in animal models have shown promising results, more research in humans is needed to determine its safety for treating arthritis

Additionally, 5-HT exerts both anti-inflammatory and pro-inflammatory effects under intestinal inflammatory conditions by binding to different receptors, and demonstrates biological functions in systems beyond the gut, such as in autism and depression

Furthermore, ZnONPs positively influenced intestinal morphology and increased Zn concentrations in plasma and tissues, while exhibiting comparable effects on serum enzymes and intestinal health indicators to those of the combined CS and ZnO treatment (Wang et al

Di Dato C, Gianfrilli D, Greco E, Astolfi M, Canepari S, Lenzi A, Isidori AM, Giannetta E

& Pekowska, A