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9 Materials and methods A structured literature review (PRISMA 2020) was conducted across PubMed, Embase, Cochrane Library, Scopus, and Google Scholar to 31 January 2026
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Glucose and G6P are proposed to be direct activators of LXR, which in turn would lead to the activation of SREBP-1c to promote the expression of lipid and cholesterol synthesis genes (226)
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