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Description
When activated, this NEMO-dependent IKK complex phosphorylates IB at Ser32 and Ser36, and induces the ubiquitination of protein and the degradation of the proteasome, releasing the inhibitory effect of IB on NF-B [72]
It is derived from glucose, a common carbohydrate (sugar) that is the primary source of energy for cells

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Additionally, retatrutide improved glycemic control, with notable reductions in HbA1c levels among participants with type 2 diabetes
(Marks, Vaccaro, Hozack, Booth, Rothman, Balderston)
