what does glutathione peroxidase contain Selenocysteine containing biosynthesis model Glutathione peroxidase (GPx) redox cycle.
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SantonocitoSPolizziAMarchettiEDalessandriDMiglioratiMLupiSMet al
[DOI] [PMC free article] [PubMed] [Google Scholar] 342.Ying A.F., Khan S., Wu Y., Jin A., Wong A.S., Tan E.K., et al
A well-functioning methylation cycle generates the amino acid cysteine, which you can read more about here
doi: 10.1038/s41401-019-0301-1 Summary Keywords high glucose, osteogenic differentiation, ROS, NADPH, periodontal tissue regeneration Citation Zhang Y, An Y, Sun L-J, Qu H-L, Li X, He X-T, Wu R-X, Chen F-M, Tian B-M and Yin Y (2023) NADPH-dependent ROS accumulation contributes to the impaired osteogenic differentiation of periodontal ligament stem cells under high glucose conditions
The impaired function of the mitochondrial respiratory chain leads to overproduction of ROS and cytokines, which triggers lipid peroxidation
