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(2000) showed that daily oral administration of 500 g/kg body weight to obese Zucker rats for 19 days resulted in over 50% reduction in body weight gain (15.8 0.6 g vs

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Research Concentration: In murine models, daily research dosages typically range from 20mg/kg to 30mg/kg of body weight to assess metabolic shifts over a 46 week cycle

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The label and Phase III trials started patients at the full dose on day one
