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Despite the high variability, the ADSC-EVs display an approximately 10% increase in wound closure rate compared to the control [138]

Peptide aggregation is the other major stability concern

38 By contrast to the studies which used purified toxins, the isolation of these variant strains suggested that TcdA was not essential for CDI onset and that strains producing only TcdB were equally as virulent as strains producing both toxins in human patients

All statistical tests were two-sided and used a significance level of P 4000 observations additionally including an additional sample with data collected in subjects still available at 6-year follow-up