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glutathione reaction mechanism Metabolism - an overview Glutathione Conjugation!
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doi: 10.3390/metabo13050586, 21
The physiological GSH:GSSG ratio is not able to promote the formation of PSSG

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Thus, residues Tyr110 and Lys105 might share a function in accordance with the glutathione activator model but might also differ, for example, regarding the protonation state of the active site cysteine residue
