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Among these proteins, iron transporters play a crucial role in controlling iron absorption, storage, distribution and overall iron homeostasis (23)

During acute inflammatory conditions, this increase in hemichannel activity may be beneficial for mounting an immune response to an insult, however, the prolonged release of many factors (i.e., glutamate) from astrocytes in chronic conditions may be associated with altered synaptic plasticity and memory impairments (Navarrete and Araque, 2010
