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For individuals sourcing either compound from unregulated online vendors, additional risks include contamination with unknown substances, incorrect dosing due to inaccurate labelling, and the use of non-sterile injection equipment, which can lead to serious infections including abscess formation or sepsis

The mechanism of itaconate-mediated inhibition of these enzymes is via alkylation of cysteine residues as well as by acylation of lysine residues

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[1] Despite being non-essential, glycine plays critical roles in normal physiology