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BACH1 equilibrates the levels of globin and heme through repressing globin and HO1 in erythroblasts upon iron lacking, Accurately adapting erythroblasts to iron deficiency and preventing toxic accumulation of nonheme globin are dependent on the ironhemeBACH1 axis
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Moreover, ROS accumulation was more obvious after 24h in vitro culture, so we chose oocyte aging for 24 hours to detect the efficiency of Epitalon scavenging ROS in vitro
mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation
