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Valproic acid may be especially useful in older patients due to its low risk of hypotension, respiratory depression, or sedation

Tsokos GC, Lo MS, Costa Reis P, Sullivan KE (2016) New insights into the immunopathogenesis of systemic lupus erythematosus

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Our previous studies have reported similar evidence in hepatocytes with low B12 demonstrating upregulation of FA and TG synthesis [14], and increased adiposity via hypomethylation and upregulation of the master regulators of lipogenesis (SREBF1) and cholesterologenesis (LDLR) in adipocytes [13]