glutathione reductase uses nadph to reduce gssg to gsh reaction - an overview Glutathione-Related Enzymes and Proteins: A

These behavioral benefits are underpinned by its marked ability to induce spinogenesis and promote functional synaptogenesis in hippocampal neurons, highlighting its potential as a robust procognitive and antidementia agent [1]

doi:10.1016/j.gene.2022.146663 Langan RC, Goodbred AJ

Introduction Neurodegenerative diseases such as Alzheimers disease (AD), Parkinsons disease (PD), and multiple sclerosis (MS) are characterized by progressive nerve damage and chronic inflammation

Thats especially the case for those containing hydroquinone, which you can read more about here

Methylcobalamin and lipotropic amino acids begin degrading within 28 hours at room temperature, with degradation accelerating significantly above 25C