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It is caused by a mutation of CDAN3, located on chromosome 15q21-q25

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When these cells become activated, they release various stimulatory molecules

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Establishment of normal concentrations of NAD and Glutathione forms in Whole Blood Next, we applied our profiling methodology to define human population values of the six redox metabolites using frozen whole blood samples from 299 anonymous healthy donors (191 females and 108 males, aged 18-70 years) provided by the Finnish Blood Service BioBank and 38 healthy in-house volunteers