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Description
Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES)
Numerous antioxidant compounds have been studied in animal models to assess their impact on NA-AION-related oxidative stress (online supplement, Table 3)
Crystal structure of human MTH1 and the 8-oxo-dGMP product complex

Though many immunotherapeutic agents targeting CTLA4 or the PD1/PD-L1 axis have been launched into the clinics for cancer treatment, accumulating clinical evidence has suggested that anti-CTLA4 and anti-PD1 are largely futile in eradicating secondary tumors and extending the lifespan of metastatic cancer patients, due to inherent or acquired drug resistance [303]

doi: 10.1055/s-0035-1548790 143 JamilianMRazaviMFakhrie KashanZGhandiYBagherianTAsemiZ