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Jia YF, Wininger K, Peyton L, Ho AM, Choi DS

Biochemistry (1998) 37:42807.10.1021/bi972863j 28 JarvisMFGessnerGWLyCG

6 Discussion DM is a metabolic disorder that induces multi-organ complications primarily through neuropathy and vascular damage, with significant adverse effects on the male reproductive system (107109)

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Later in the infection, the combination of signals and pathways induced for bacterial internalization may promote a localized loss of barrier function, allowing the paracellular route to occur, making bacterial internalization a requisite step for further invasion