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In addition, TMAO induces several inflammatory pathways, which cause the activation of pro-inflammatory cytokines such as IL-6 and TNF- which causes chronic inflammation thereby causing plaque formation and plaque rupture leading to cardiovascular disease [71]

Cleaving the backbone carbonnitrogen bond An alternative pathway to use carnitine as a sole carbon source is to cleave the carbonnitrogen bond of carnitine to form trimethylamine and malic acid

doi: 10.1038/s42255-019-0055-6 114 PourseyediNArefhosseiniSTutunchiHEbrahimi-MameghaniM

A taurina foi isolada pela primeira vez a partir da bile bovina, em 1827, o que gerou seu nome

As a cofactor facilitating the metabolism of fatty acids in the mitochondria, ALC is helpful in reducing insulin resistance and has also been found to improve chemotherapy-induced and HIV-associated neuropathy 7,8