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Notably, although an increased number of blood vessels was found within the wound, angiogenesis did not significantly change in terms of vessel density or size, suggesting that the beneficial effect of QHREDGS was mainly due to keratinocyte stimulation rather than direct vascular effects

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Acknowledgments I would like to thank B-RX (The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui Provincial Cancer Hospital) for advice and useful comments that helped finalize this review article