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Algunos estudios han sugerido que las personas con fibromialgia pueden tener niveles reducidos de antioxidantes, incluido el glutatin, en comparacin con individuos sanos
Although Alox5 was differentially expressed in the RNA-seq dataset, Slc7a11, Gpx4, and Nrf2 did not meet significance thresholds, likely reflecting differences in assay sensitivity or the limited RNA-seq sample size
2.3 Failure of antioxidant system Nuclear factor erythroid 2-related factor 2 (NRF2) orchestrates cellular antioxidant defense by directly regulating glutathione (GSH) biosynthesis and GPX4 expression through transcriptional control of Glutamate-Cysteine Ligase Catalytic Subunit(GCLC)/ Glutamate-Cysteine Ligase Modifier Subunit(GCLM) and GPX4 (Fan et al., 2024)
doi:10.1002/rmb2.12326
Applying the 2017 McDonald diagnostic criteria for multiple sclerosis Authors reply
