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Encephalopathy and neuropathy following ingestion of a Chinese herbal broth containing podophyllin

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An estimated 35,000 abdominal myomectomies are performed annually for fibroids in American women

Therefore, cellular iron is tightly regulated at multiple nodes, involving different forms of iron: Fe-S clusters (IRE-IRP), iron ions (PHD-HIF and KDM3B-mTOR-TTP) and haem (HRI)

This leads to the cytosolic release of mtDNA, triggering inflammatory cascades and worsening mitochondrial damage
