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Further highlighting the functional relationship between Ec CnoX and GroEL/ES, GroEL/ES obligate substrates are over-represented in the proteins found in a mixed-disulfide complex with Ec CnoX (Goemans et al., 2018b)

BDNF downregulation using heterozygous mice leads to opposite effects on serotonin by reduced hippocampal SERT activity, and these effects were observed to be region-specific [200]

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T cell exhaustion has not been associated with tumoral GPX4 expression, but as our DIO study indicated greater numbers of PD1+/TIM3 + CD8 + T cells in shGPX4 tumors, this finding could be a diet-specific effect