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Additionally, it decreased the expression of pro-inflammatory cytokines and inhibited the phosphorylation of STAT3, a key pathway involved in psoriasis pathogenesis [106]

S., Oliveri, M

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Studies with complete reporting and rigorous design were rated as "High," while others with some limitations or missing methodological details were rated as "Medium" or "Low." To evaluate the reliability and scientific rigor of the evidence presented in this review, we conducted a methodological quality assessment of the primary clinical trials included

Beyond the bioenergetic defects, damaged mtDNA may leak from mitochondria into the cytoplasm or extracellular space [31]
