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Elevated levels or unnaturally low levels of Krebs cycle metabolites also indicate mitochondrial dysfunction, often stemming from deficiencies in various nutrients and enzymes that are vital to the health of your mitochondria

3 Notably, the hippocampus plays an important role in executive function and memory performance suggesting that the hippocampus has a role in PD

[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Ganote C.E., Peterson D.R., Carone F.A

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Cells were transfected with siRNA and then treated with 5.6 mM glucose or 25 mM glucose for 72 hours: A: siRNA enhanced cell proliferation under high glucose conditions B: siRNA decreased apoptosis under high glucose conditions