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Biochim Biophys Acta (2000) 1488:119

This pathway increases NO production, essential for endothelial proliferation, vessel dilation, and new capillary formation, which may be particularly beneficial in ischemic or hypovascular musculoskeletal tissues [20, 24, 26, 39, 41]

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Elucidation of the GSK3alpha Structure Informs the Design of Novel, Paralog-Selective Inhibitors