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Along with IPS and CSCs, the idea has been expanded to include ESCs and adult stem cells

SPSS 21.0 software (Chicago, IL) was used for the statistical analyses

There is growing consensus regarding their pathophysiology and management, but more work is needed to elucidate the relationships between irAEs and treatment outcomes, specific biomarkers that clinch an irAE diagnosis, the impact of tailored immunosuppression on ICI outcomes, and the management of steroid-refractory irAEs

In addition to investigating disease-specific factors, research should also prioritize the identification of the most suitable stem cell source for treating specific conditions

The analyzed studies indicate that natural antioxidants have a high level of efficacy in the treatment of MAFLD (100%)