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During a healthy pregnancy, the upregulation of regulatory T (Treg) cells and T-helper type 2 (Th2) cells represent a major maternal adaptation that helps with embryo implantation and the maintenance of pregnancy [19-21]

Thein-Han W, Liu J, Xu HH

The figure is biologically attractive and genetically coherent, but no primary-prevention trial has tested whether treating healthy adults to below 0.6 g/L produces better outcomes than current practice