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Patients with long-standing alcohol use, restrictive diets, malabsorption syndromes, or prolonged use of medications that deplete or interfere with B vitamins may particularly benefit when a deficiency is confirmed

This research raises the question of whether people who are taking acid-depressing medications long term should be screened for vitamin B12 deficiency, Dr

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B12 injections can be mildly painful for some however most patients can tolerate the discomfort well