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No significant toxicity has been identified in animal studies even at doses far exceeding typical human protocols
[DOI] [PMC free article] [PubMed] [Google Scholar] 365.van Dijk, A

In such cases, the NHS standard treatment is intramuscular hydroxocobalamin injections, typically given every 2-3 months for maintenance after an initial loading regimen

I.Perez-LuqueE.Ibarra-ReynosoL.Gallardo-BlancoH

Stasis of the submucosal blood vessels was also present (Figure 25A)
