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In males, ROS are involved in sperm capacitation through cholesterol efflux, membrane hyperpolarization, and tyrosine phosphorylationprerequisites for acrosomal exocytosis and zona pellucida binding (49, 51, 52)

2020;319:F1105F1116

Strength quantifies the direct number and weight of connections, while expected influence (EI) extends this by also considering the influence of a nodes connections beyond its immediate neighbors 23

MMP inhibition: GHK-Cu suppresses MMP-1 (interstitial collagenase) and MMP-9 (gelatinase B) expression in cultured fibroblasts, reducing collagen degradation alongside synthesis promotion

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