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Description
The sixth coordination site, the reactive center, is variable, being a cyano group (CN), a hydroxyl group (OH), a methyl group (CH 3 ) or a 5-deoxyadenosyl group

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Folate deficiency during pregnancy increases the likelihood of birthing babies with spina bifida, a neural birth defect occurring when a babys spinal cord does not develop properly, causing a gap in the spine

Haptocorrin bound to B12 keeps it from being damaged in stomach acid
