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While mouse models are invaluable for their low cost, rapid breeding cycle, and genetic tractability, their primary limitation is the failure to spontaneously develop human-like lung disease, which is the main cause of morbidity in patients

Ortiz-Prado, E., Dunn, J

Additionally, there is sufficient evidence to show their immunomodulatory properties and the capacity of ectopic formation in vivo [43]

Once the acute flare resolves, patients with recurrent attacks may be started on urate-lowering therapy, such as the competitive inhibitor allopurinol , to prevent future episodes

Mitochondrial DNA abnormalities and autistic spectrum disorders