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NICE obesity guidance recommends evidence-based interventions including dietary change, physical activity, and licensed medications such as orlistat or semaglutide

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Clin Cancer Res 20:45744583 Lammerts van Bueren J, Jakobs D, Kaldenhoven N, Roza M, Hiddingh S, Meesters J et al (2014) Direct in vitro comparison of daratumumab with surrogate analogs of CD38 antibodies MOR03087, SAR650984 and Ab79
