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J Cell Biochem (1994) 55 Suppl:5465

In the proximal ileum, B 12 is released to bind to the gastric intrinsic factor, which is a B 12 -transfer protein essential for ileal cobalamin absorption

The injection site can become red or slightly inflamed (red slight bump) afterward and this is nothing to be concerned over

But patterns that emerge across many independent users can suggest real phenomena worth investigating

They found that it wasnt possible to determine a clear lower limit for which any of these biomarkers can reliably indicate B12 deficiency, but that daily intakes above 4.0 g appear to have no additional benefit