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Finally, lipolysis increase, high free FA flow to the liver, pro-inflammatory cytokines rise, FA oxidation dysregulation and de novo lipogenesis, are common features in both ethanol-induced liver injury and non-alcoholic fatty liver disease (NAFLD) (62)

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Increasingly, human trials demonstrate distinct responder and non-responder subgroups, even when participants receive the same strain and dosage, with differences correlated to baseline microbial community structures, metabolic profiles, and gut transit characteristics (573)
Cell Death Differ 14:12111221 Dieck ST, Heuer H, Ehrchen J, Otto C, Bauer K (1999) The peptide transporter PepT2 is expressed in rat brain and mediates the accumulation of the fluorescent dipeptide derivative beta-Ala-Lys-Nepsilon-AMCA in astrocytes
